A simple and inexpensive method for sending binary vector plasmid DNA by mail

We describe a simple cost-effective technique for the transport of binary vector plasmid DNA by mail. Our results demonstrate that common multipurpose printing paper is a satisfactory substrate and superior to the more absorbent 3 MM chromatography paper for the transport of plasmid DNA through the mail. We show that depositing as little as 100 ng of purified plasmid onto multipurpose printing paper is sufficient to allow recovery of the mailed DNA. Also observed was an inverse correlation between vector size and recovery of intact plasmid DNA, thus larger binary vectors require the deposition of more plasmid to ensure successful recovery.